The worldwide nutritional transition to a standard “Western diet” that has occurred over the last 1-2 decades has resulted in an epidemic of obesity and type 2 diabetes and the myriad co-morbidities associated with those diseases such as coronary heart disease, hypertension, and cancer. It is estimated that 1 in 3 to 1 in 5 Americans are obese depending on the definition of obesity, and that over 17 million Americans have been diagnosed with diabetes with a rapidly rising incidence especially among the young. The recognition of obesity as a major health problem is reflected by the fact that obesity has a stronger association with chronic medical conditions, reduced quality of life, and increased health costs than smoking or drinking and that this association is similar to the impact of 20 years of aging.

Besides storing and releasing energy for whole body use, adipocytes (fat cells) act as an endocrine organ capable of responding to and secreting active peptides. Thus, adipocytes act as a critical determinant of where fats will be used, when and how they will be metabolized.

Most importantly, the different types of fat can have unique effects. It has been known for some time that different dietary fats appear to have varying effects on insulin-sensitive tissues and this may affect the expression of glucose tolerance (an important determinant of diabetes and obesity).

Numerous studies have demonstrated that the ingestion of fats rich in n-6 (omega-6) and n-3 (omega-3) fatty acids, the so-called 18:2 fatty acids, suppress fatty acid biosynthesis in the liver, triglyceride production, and triglyceride secretion, while they enhance hepatic, adipose, and skeletal muscle metabolism; this is not observed by the addition of saturated fatty acids.

Furthermore, it was demonstrated that the insulin resistance in rats fed a high-fat diet was prevented when saturated, monounsaturated, and omega-6 polyunsaturated fatty acids were partially replaced with omega-3 polyunsaturated fatty acids as is found in fish oils.

There also appears to be a further difference between omega-3 and omega-6 fatty acids as demonstrated in another study where rats fed a diet rich in omega-3 fatty acids displayed evidence of normal insulin signaling whereas rats fed a omega-6 high-fat diet did not.

These types of fat are metabolized to highly unsaturated fatty acid, which can suppress genes involved in fat synthesis while inducing genes necessary for fata and energy metabolism.

The take home message is that all fat is not created equally and that fat is not the root cause of the obesity and diabetic epidemic in modern society. Instead, ingestion (and supplementation) of the right kinds of fats can, in fact, be protective and reverse these modern syndromes. This is the primary fact as to why Metabolic Health Labs promotes the use of Krill Oil Supplements. More information regarding Krill Oil is provided on our website.

In addition, future discussions will focus exclusively on Krill Oil and the components found within this supplement.

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